School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.
Identifieur interne : 001074 ( Main/Exploration ); précédent : 001073; suivant : 001075School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.
Auteurs : Danuta Wasserman [Suède] ; Christina W. Hoven [États-Unis] ; Camilla Wasserman [Italie] ; Melanie Wall [États-Unis] ; Ruth Eisenberg [États-Unis] ; Gergö Hadlaczky [Suède] ; Ian Kelleher [Suède] ; Marco Sarchiapone [Italie] ; Alan Apter [Israël] ; Judit Balazs [Hongrie] ; Julio Bobes [Espagne] ; Romuald Brunner [Allemagne] ; Paul Corcoran [Irlande (pays)] ; Doina Cosman [Roumanie] ; Francis Guillemin [France] ; Christian Haring [Autriche] ; Miriam Iosue [Italie] ; Michael Kaess [Allemagne] ; Jean-Pierre Kahn [France] ; Helen Keeley [Irlande (pays)] ; George J. Musa [États-Unis] ; Bogdan Nemes [Roumanie] ; Vita Postuvan [Slovénie] ; Pilar Saiz [Espagne] ; Stella Reiter-Theil [Suisse] ; Airi Varnik [Estonie] ; Peeter Varnik [Estonie] ; Vladimir Carli [Suède]Source :
- Lancet (London, England) [ 1474-547X ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Analyse de regroupements (MeSH), Autorapport (MeSH), Europe (MeSH), Femelle (MeSH), Humains (MeSH), Mâle (MeSH), Services de santé scolaire (MeSH), Suicide (prévention et contrôle), Suicide (statistiques et données numériques), Éducation pour la santé (MeSH), Études de suivi (MeSH), Évaluation de programme (MeSH).
- MESH :
- prévention et contrôle : Suicide.
- statistiques et données numériques : Suicide.
- Adolescent, Analyse de regroupements, Autorapport, Europe, Femelle, Humains, Mâle, Services de santé scolaire, Éducation pour la santé, Études de suivi, Évaluation de programme.
English descriptors
- KwdEn :
- Adolescent (MeSH), Cluster Analysis (MeSH), Europe (MeSH), Female (MeSH), Follow-Up Studies (MeSH), Health Education (MeSH), Humans (MeSH), Male (MeSH), Outcome Assessment, Health Care (MeSH), Program Evaluation (MeSH), School Health Services (MeSH), Self Report (MeSH), Suicide (prevention & control), Suicide (statistics & numerical data).
- MESH :
- geographic : Europe.
- prevention & control : Suicide.
- statistics & numerical data : Suicide.
- Adolescent, Cluster Analysis, Female, Follow-Up Studies, Health Education, Humans, Male, Outcome Assessment, Health Care, Program Evaluation, School Health Services, Self Report.
Abstract
BACKGROUND
Suicidal behaviours in adolescents are a major public health problem and evidence-based prevention programmes are greatly needed. We aimed to investigate the efficacy of school-based preventive interventions of suicidal behaviours.
METHODS
The Saving and Empowering Young Lives in Europe (SEYLE) study is a multicentre, cluster-randomised controlled trial. The SEYLE sample consisted of 11,110 adolescent pupils, median age 15 years (IQR 14-15), recruited from 168 schools in ten European Union countries. We randomly assigned the schools to one of three interventions or a control group. The interventions were: (1) Question, Persuade, and Refer (QPR), a gatekeeper training module targeting teachers and other school personnel, (2) the Youth Aware of Mental Health Programme (YAM) targeting pupils, and (3) screening by professionals (ProfScreen) with referral of at-risk pupils. Each school was randomly assigned by random number generator to participate in one intervention (or control) group only and was unaware of the interventions undertaken in the other three trial groups. The primary outcome measure was the number of suicide attempt(s) made by 3 month and 12 month follow-up. Analysis included all pupils with data available at each timepoint, excluding those who had ever attempted suicide or who had shown severe suicidal ideation during the 2 weeks before baseline. This study is registered with the German Clinical Trials Registry, number DRKS00000214.
FINDINGS
Between Nov 1, 2009, and Dec 14, 2010, 168 schools (11,110 pupils) were randomly assigned to interventions (40 schools [2692 pupils] to QPR, 45 [2721] YAM, 43 [2764] ProfScreen, and 40 [2933] control). No significant differences between intervention groups and the control group were recorded at the 3 month follow-up. At the 12 month follow-up, YAM was associated with a significant reduction of incident suicide attempts (odds ratios [OR] 0·45, 95% CI 0·24-0·85; p=0·014) and severe suicidal ideation (0·50, 0·27-0·92; p=0·025), compared with the control group. 14 pupils (0·70%) reported incident suicide attempts at the 12 month follow-up in the YAM versus 34 (1·51%) in the control group, and 15 pupils (0·75%) reported incident severe suicidal ideation in the YAM group versus 31 (1·37%) in the control group. No participants completed suicide during the study period.
INTERPRETATION
YAM was effective in reducing the number of suicide attempts and severe suicidal ideation in school-based adolescents. These findings underline the benefit of this universal suicide preventive intervention in schools.
FUNDING
Coordination Theme 1 (Health) of the European Union Seventh Framework Programme.
DOI: 10.1016/S0140-6736(14)61213-7
PubMed: 25579833
Affiliations:
- Allemagne, Autriche, Espagne, Estonie, France, Hongrie, Irlande (pays), Israël, Italie, Roumanie, Slovénie, Suisse, Suède, États-Unis
- Bade-Wurtemberg, District de Karlsruhe, Grand Est, Hongrie centrale, Latium, Lorraine (région), Svealand, État de New York
- Budapest, Heidelberg, Nancy, New York, Rome, Stockholm
- Université Columbia
Links toward previous steps (curation, corpus...)
Le document en format XML
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and Health Science, University of Molise, Campobasso, Italy; National Institute for Health, Migration and Poverty, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine and Health Science, University of Molise, Campobasso, Italy; National Institute for Health, Migration and Poverty, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Apter, Alan" sort="Apter, Alan" uniqKey="Apter A" first="Alan" last="Apter">Alan Apter</name><affiliation wicri:level="1"><nlm:affiliation>Feinberg Child Study Centre, Schneider Children's Medical Centre, Tel Aviv University, Tel Aviv, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Feinberg Child Study Centre, Schneider Children's Medical Centre, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Balazs, Judit" sort="Balazs, Judit" uniqKey="Balazs J" first="Judit" last="Balazs">Judit Balazs</name><affiliation wicri:level="3"><nlm:affiliation>Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Bobes, Julio" sort="Bobes, Julio" uniqKey="Bobes J" first="Julio" last="Bobes">Julio Bobes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Brunner, Romuald" sort="Brunner, Romuald" uniqKey="Brunner R" first="Romuald" last="Brunner">Romuald Brunner</name><affiliation wicri:level="3"><nlm:affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Corcoran, Paul" sort="Corcoran, Paul" uniqKey="Corcoran P" first="Paul" last="Corcoran">Paul Corcoran</name><affiliation wicri:level="1"><nlm:affiliation>National Suicide Research Foundation, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National Suicide Research Foundation, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Cosman, Doina" sort="Cosman, Doina" uniqKey="Cosman D" first="Doina" last="Cosman">Doina Cosman</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca</wicri:regionArea><wicri:noRegion>Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Guillemin, Francis" sort="Guillemin, Francis" uniqKey="Guillemin F" first="Francis" last="Guillemin">Francis Guillemin</name><affiliation wicri:level="3"><nlm:affiliation>Inserm CIC-EC, Nancy University Hospital, Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm CIC-EC, Nancy University Hospital, Nancy</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Haring, Christian" sort="Haring, Christian" uniqKey="Haring C" first="Christian" last="Haring">Christian Haring</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Clinical Evaluation, Department for Psychiatry and Psychotherapy B, State Hospital Hall, Tyrol, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute for Clinical Evaluation, Department for Psychiatry and Psychotherapy B, State Hospital Hall, Tyrol</wicri:regionArea><wicri:noRegion>Tyrol</wicri:noRegion></affiliation></author><author><name sortKey="Iosue, Miriam" sort="Iosue, Miriam" uniqKey="Iosue M" first="Miriam" last="Iosue">Miriam Iosue</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine and Health Science, University of Molise, Campobasso, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine and Health Science, University of Molise, Campobasso</wicri:regionArea><wicri:noRegion>Campobasso</wicri:noRegion></affiliation></author><author><name sortKey="Kaess, Michael" sort="Kaess, Michael" uniqKey="Kaess M" first="Michael" last="Kaess">Michael Kaess</name><affiliation wicri:level="3"><nlm:affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Kahn, Jean Pierre" sort="Kahn, Jean Pierre" uniqKey="Kahn J" first="Jean-Pierre" last="Kahn">Jean-Pierre Kahn</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, Nancy University Hospital, Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Psychiatry, Nancy University Hospital, Nancy</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Keeley, Helen" sort="Keeley, Helen" uniqKey="Keeley H" first="Helen" last="Keeley">Helen Keeley</name><affiliation wicri:level="1"><nlm:affiliation>National Suicide Research Foundation, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National Suicide Research Foundation, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Musa, George J" sort="Musa, George J" uniqKey="Musa G" first="George J" last="Musa">George J. Musa</name><affiliation wicri:level="4"><nlm:affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Nemes, Bogdan" sort="Nemes, Bogdan" uniqKey="Nemes B" first="Bogdan" last="Nemes">Bogdan Nemes</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca</wicri:regionArea><wicri:noRegion>Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Postuvan, Vita" sort="Postuvan, Vita" uniqKey="Postuvan V" first="Vita" last="Postuvan">Vita Postuvan</name><affiliation wicri:level="1"><nlm:affiliation>Slovene Center for Suicide Research, Andrej Marusic Institute, University of Primorska, Koper, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>Slovene Center for Suicide Research, Andrej Marusic Institute, University of Primorska, Koper</wicri:regionArea><wicri:noRegion>Koper</wicri:noRegion></affiliation></author><author><name sortKey="Saiz, Pilar" sort="Saiz, Pilar" uniqKey="Saiz P" first="Pilar" last="Saiz">Pilar Saiz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Reiter Theil, Stella" sort="Reiter Theil, Stella" uniqKey="Reiter Theil S" first="Stella" last="Reiter-Theil">Stella Reiter-Theil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Ethics, Psychiatric Hospitals of the University of Basel, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Clinical Ethics, Psychiatric Hospitals of the University of Basel, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Varnik, Airi" sort="Varnik, Airi" uniqKey="Varnik A" first="Airi" last="Varnik">Airi Varnik</name><affiliation wicri:level="1"><nlm:affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn</wicri:regionArea><wicri:noRegion>Tallinn</wicri:noRegion></affiliation></author><author><name sortKey="Varnik, Peeter" sort="Varnik, Peeter" uniqKey="Varnik P" first="Peeter" last="Varnik">Peeter Varnik</name><affiliation wicri:level="1"><nlm:affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn</wicri:regionArea><wicri:noRegion>Tallinn</wicri:noRegion></affiliation></author><author><name sortKey="Carli, Vladimir" sort="Carli, Vladimir" uniqKey="Carli V" first="Vladimir" last="Carli">Vladimir Carli</name><affiliation wicri:level="3"><nlm:affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25579833</idno><idno type="pmid">25579833</idno><idno type="doi">10.1016/S0140-6736(14)61213-7</idno><idno type="wicri:Area/Main/Corpus">001137</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001137</idno><idno type="wicri:Area/Main/Curation">001137</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001137</idno><idno type="wicri:Area/Main/Exploration">001137</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.</title><author><name sortKey="Wasserman, Danuta" sort="Wasserman, Danuta" uniqKey="Wasserman D" first="Danuta" last="Wasserman">Danuta Wasserman</name><affiliation wicri:level="3"><nlm:affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden. Electronic address: danuta.wasserman@ki.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hoven, Christina W" sort="Hoven, Christina W" uniqKey="Hoven C" first="Christina W" last="Hoven">Christina W. Hoven</name><affiliation wicri:level="4"><nlm:affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Wasserman, Camilla" sort="Wasserman, Camilla" uniqKey="Wasserman C" first="Camilla" last="Wasserman">Camilla Wasserman</name><affiliation wicri:level="4"><nlm:affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Medicine and Health Science, University of Molise, Campobasso, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Medicine and Health Science, University of Molise, Campobasso</wicri:regionArea><orgName type="university">Université Columbia</orgName><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Wall, Melanie" sort="Wall, Melanie" uniqKey="Wall M" first="Melanie" last="Wall">Melanie Wall</name><affiliation wicri:level="4"><nlm:affiliation>Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Eisenberg, Ruth" sort="Eisenberg, Ruth" uniqKey="Eisenberg R" first="Ruth" last="Eisenberg">Ruth Eisenberg</name><affiliation wicri:level="4"><nlm:affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Hadlaczky, Gergo" sort="Hadlaczky, Gergo" uniqKey="Hadlaczky G" first="Gergö" last="Hadlaczky">Gergö Hadlaczky</name><affiliation wicri:level="3"><nlm:affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Kelleher, Ian" sort="Kelleher, Ian" uniqKey="Kelleher I" first="Ian" last="Kelleher">Ian Kelleher</name><affiliation wicri:level="3"><nlm:affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Sarchiapone, Marco" sort="Sarchiapone, Marco" uniqKey="Sarchiapone M" first="Marco" last="Sarchiapone">Marco Sarchiapone</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine and Health Science, University of Molise, Campobasso, Italy; National Institute for Health, Migration and Poverty, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine and Health Science, University of Molise, Campobasso, Italy; National Institute for Health, Migration and Poverty, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Apter, Alan" sort="Apter, Alan" uniqKey="Apter A" first="Alan" last="Apter">Alan Apter</name><affiliation wicri:level="1"><nlm:affiliation>Feinberg Child Study Centre, Schneider Children's Medical Centre, Tel Aviv University, Tel Aviv, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Feinberg Child Study Centre, Schneider Children's Medical Centre, Tel Aviv University, Tel Aviv</wicri:regionArea><wicri:noRegion>Tel Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Balazs, Judit" sort="Balazs, Judit" uniqKey="Balazs J" first="Judit" last="Balazs">Judit Balazs</name><affiliation wicri:level="3"><nlm:affiliation>Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Budapest, Hungary.</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Bobes, Julio" sort="Bobes, Julio" uniqKey="Bobes J" first="Julio" last="Bobes">Julio Bobes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Brunner, Romuald" sort="Brunner, Romuald" uniqKey="Brunner R" first="Romuald" last="Brunner">Romuald Brunner</name><affiliation wicri:level="3"><nlm:affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Corcoran, Paul" sort="Corcoran, Paul" uniqKey="Corcoran P" first="Paul" last="Corcoran">Paul Corcoran</name><affiliation wicri:level="1"><nlm:affiliation>National Suicide Research Foundation, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National Suicide Research Foundation, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Cosman, Doina" sort="Cosman, Doina" uniqKey="Cosman D" first="Doina" last="Cosman">Doina Cosman</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca</wicri:regionArea><wicri:noRegion>Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Guillemin, Francis" sort="Guillemin, Francis" uniqKey="Guillemin F" first="Francis" last="Guillemin">Francis Guillemin</name><affiliation wicri:level="3"><nlm:affiliation>Inserm CIC-EC, Nancy University Hospital, Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm CIC-EC, Nancy University Hospital, Nancy</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Haring, Christian" sort="Haring, Christian" uniqKey="Haring C" first="Christian" last="Haring">Christian Haring</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Clinical Evaluation, Department for Psychiatry and Psychotherapy B, State Hospital Hall, Tyrol, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute for Clinical Evaluation, Department for Psychiatry and Psychotherapy B, State Hospital Hall, Tyrol</wicri:regionArea><wicri:noRegion>Tyrol</wicri:noRegion></affiliation></author><author><name sortKey="Iosue, Miriam" sort="Iosue, Miriam" uniqKey="Iosue M" first="Miriam" last="Iosue">Miriam Iosue</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine and Health Science, University of Molise, Campobasso, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine and Health Science, University of Molise, Campobasso</wicri:regionArea><wicri:noRegion>Campobasso</wicri:noRegion></affiliation></author><author><name sortKey="Kaess, Michael" sort="Kaess, Michael" uniqKey="Kaess M" first="Michael" last="Kaess">Michael Kaess</name><affiliation wicri:level="3"><nlm:affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Kahn, Jean Pierre" sort="Kahn, Jean Pierre" uniqKey="Kahn J" first="Jean-Pierre" last="Kahn">Jean-Pierre Kahn</name><affiliation wicri:level="3"><nlm:affiliation>Department of Psychiatry, Nancy University Hospital, Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Psychiatry, Nancy University Hospital, Nancy</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Keeley, Helen" sort="Keeley, Helen" uniqKey="Keeley H" first="Helen" last="Keeley">Helen Keeley</name><affiliation wicri:level="1"><nlm:affiliation>National Suicide Research Foundation, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>National Suicide Research Foundation, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Musa, George J" sort="Musa, George J" uniqKey="Musa G" first="George J" last="Musa">George J. Musa</name><affiliation wicri:level="4"><nlm:affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Nemes, Bogdan" sort="Nemes, Bogdan" uniqKey="Nemes B" first="Bogdan" last="Nemes">Bogdan Nemes</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca</wicri:regionArea><wicri:noRegion>Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Postuvan, Vita" sort="Postuvan, Vita" uniqKey="Postuvan V" first="Vita" last="Postuvan">Vita Postuvan</name><affiliation wicri:level="1"><nlm:affiliation>Slovene Center for Suicide Research, Andrej Marusic Institute, University of Primorska, Koper, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>Slovene Center for Suicide Research, Andrej Marusic Institute, University of Primorska, Koper</wicri:regionArea><wicri:noRegion>Koper</wicri:noRegion></affiliation></author><author><name sortKey="Saiz, Pilar" sort="Saiz, Pilar" uniqKey="Saiz P" first="Pilar" last="Saiz">Pilar Saiz</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Reiter Theil, Stella" sort="Reiter Theil, Stella" uniqKey="Reiter Theil S" first="Stella" last="Reiter-Theil">Stella Reiter-Theil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Ethics, Psychiatric Hospitals of the University of Basel, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Clinical Ethics, Psychiatric Hospitals of the University of Basel, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Varnik, Airi" sort="Varnik, Airi" uniqKey="Varnik A" first="Airi" last="Varnik">Airi Varnik</name><affiliation wicri:level="1"><nlm:affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn</wicri:regionArea><wicri:noRegion>Tallinn</wicri:noRegion></affiliation></author><author><name sortKey="Varnik, Peeter" sort="Varnik, Peeter" uniqKey="Varnik P" first="Peeter" last="Varnik">Peeter Varnik</name><affiliation wicri:level="1"><nlm:affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn</wicri:regionArea><wicri:noRegion>Tallinn</wicri:noRegion></affiliation></author><author><name sortKey="Carli, Vladimir" sort="Carli, Vladimir" uniqKey="Carli V" first="Vladimir" last="Carli">Vladimir Carli</name><affiliation wicri:level="3"><nlm:affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="eISSN">1474-547X</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Cluster Analysis (MeSH)</term><term>Europe (MeSH)</term><term>Female (MeSH)</term><term>Follow-Up Studies (MeSH)</term><term>Health Education (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Outcome Assessment, Health Care (MeSH)</term><term>Program Evaluation (MeSH)</term><term>School Health Services (MeSH)</term><term>Self Report (MeSH)</term><term>Suicide (prevention & control)</term><term>Suicide (statistics & numerical data)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Analyse de regroupements (MeSH)</term><term>Autorapport (MeSH)</term><term>Europe (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Services de santé scolaire (MeSH)</term><term>Suicide (prévention et contrôle)</term><term>Suicide (statistiques et données numériques)</term><term>Éducation pour la santé (MeSH)</term><term>Études de suivi (MeSH)</term><term>Évaluation de programme (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Europe</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Suicide</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Suicide</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Suicide</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Suicide</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Cluster Analysis</term><term>Female</term><term>Follow-Up Studies</term><term>Health Education</term><term>Humans</term><term>Male</term><term>Outcome Assessment, Health Care</term><term>Program Evaluation</term><term>School Health Services</term><term>Self Report</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Analyse de regroupements</term><term>Autorapport</term><term>Europe</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Services de santé scolaire</term><term>Éducation pour la santé</term><term>Études de suivi</term><term>Évaluation de programme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Suicidal behaviours in adolescents are a major public health problem and evidence-based prevention programmes are greatly needed. We aimed to investigate the efficacy of school-based preventive interventions of suicidal behaviours.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>The Saving and Empowering Young Lives in Europe (SEYLE) study is a multicentre, cluster-randomised controlled trial. The SEYLE sample consisted of 11,110 adolescent pupils, median age 15 years (IQR 14-15), recruited from 168 schools in ten European Union countries. We randomly assigned the schools to one of three interventions or a control group. The interventions were: (1) Question, Persuade, and Refer (QPR), a gatekeeper training module targeting teachers and other school personnel, (2) the Youth Aware of Mental Health Programme (YAM) targeting pupils, and (3) screening by professionals (ProfScreen) with referral of at-risk pupils. Each school was randomly assigned by random number generator to participate in one intervention (or control) group only and was unaware of the interventions undertaken in the other three trial groups. The primary outcome measure was the number of suicide attempt(s) made by 3 month and 12 month follow-up. Analysis included all pupils with data available at each timepoint, excluding those who had ever attempted suicide or who had shown severe suicidal ideation during the 2 weeks before baseline. This study is registered with the German Clinical Trials Registry, number DRKS00000214.</p></div><div type="abstract" xml:lang="en"><p><b>FINDINGS</b></p><p>Between Nov 1, 2009, and Dec 14, 2010, 168 schools (11,110 pupils) were randomly assigned to interventions (40 schools [2692 pupils] to QPR, 45 [2721] YAM, 43 [2764] ProfScreen, and 40 [2933] control). No significant differences between intervention groups and the control group were recorded at the 3 month follow-up. At the 12 month follow-up, YAM was associated with a significant reduction of incident suicide attempts (odds ratios [OR] 0·45, 95% CI 0·24-0·85; p=0·014) and severe suicidal ideation (0·50, 0·27-0·92; p=0·025), compared with the control group. 14 pupils (0·70%) reported incident suicide attempts at the 12 month follow-up in the YAM versus 34 (1·51%) in the control group, and 15 pupils (0·75%) reported incident severe suicidal ideation in the YAM group versus 31 (1·37%) in the control group. No participants completed suicide during the study period.</p></div><div type="abstract" xml:lang="en"><p><b>INTERPRETATION</b></p><p>YAM was effective in reducing the number of suicide attempts and severe suicidal ideation in school-based adolescents. These findings underline the benefit of this universal suicide preventive intervention in schools.</p></div><div type="abstract" xml:lang="en"><p><b>FUNDING</b></p><p>Coordination Theme 1 (Health) of the European Union Seventh Framework Programme.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25579833</PMID><DateCompleted><Year>2015</Year><Month>05</Month><Day>18</Day></DateCompleted><DateRevised><Year>2019</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1474-547X</ISSN><JournalIssue CitedMedium="Internet"><Volume>385</Volume><Issue>9977</Issue><PubDate><Year>2015</Year><Month>Apr</Month><Day>18</Day></PubDate></JournalIssue><Title>Lancet (London, England)</Title><ISOAbbreviation>Lancet</ISOAbbreviation></Journal><ArticleTitle>School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.</ArticleTitle><Pagination><MedlinePgn>1536-44</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/S0140-6736(14)61213-7</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0140-6736(14)61213-7</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Suicidal behaviours in adolescents are a major public health problem and evidence-based prevention programmes are greatly needed. We aimed to investigate the efficacy of school-based preventive interventions of suicidal behaviours.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The Saving and Empowering Young Lives in Europe (SEYLE) study is a multicentre, cluster-randomised controlled trial. The SEYLE sample consisted of 11,110 adolescent pupils, median age 15 years (IQR 14-15), recruited from 168 schools in ten European Union countries. We randomly assigned the schools to one of three interventions or a control group. The interventions were: (1) Question, Persuade, and Refer (QPR), a gatekeeper training module targeting teachers and other school personnel, (2) the Youth Aware of Mental Health Programme (YAM) targeting pupils, and (3) screening by professionals (ProfScreen) with referral of at-risk pupils. Each school was randomly assigned by random number generator to participate in one intervention (or control) group only and was unaware of the interventions undertaken in the other three trial groups. The primary outcome measure was the number of suicide attempt(s) made by 3 month and 12 month follow-up. Analysis included all pupils with data available at each timepoint, excluding those who had ever attempted suicide or who had shown severe suicidal ideation during the 2 weeks before baseline. This study is registered with the German Clinical Trials Registry, number DRKS00000214.</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">Between Nov 1, 2009, and Dec 14, 2010, 168 schools (11,110 pupils) were randomly assigned to interventions (40 schools [2692 pupils] to QPR, 45 [2721] YAM, 43 [2764] ProfScreen, and 40 [2933] control). No significant differences between intervention groups and the control group were recorded at the 3 month follow-up. At the 12 month follow-up, YAM was associated with a significant reduction of incident suicide attempts (odds ratios [OR] 0·45, 95% CI 0·24-0·85; p=0·014) and severe suicidal ideation (0·50, 0·27-0·92; p=0·025), compared with the control group. 14 pupils (0·70%) reported incident suicide attempts at the 12 month follow-up in the YAM versus 34 (1·51%) in the control group, and 15 pupils (0·75%) reported incident severe suicidal ideation in the YAM group versus 31 (1·37%) in the control group. No participants completed suicide during the study period.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">YAM was effective in reducing the number of suicide attempts and severe suicidal ideation in school-based adolescents. These findings underline the benefit of this universal suicide preventive intervention in schools.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">Coordination Theme 1 (Health) of the European Union Seventh Framework Programme.</AbstractText><CopyrightInformation>Copyright © 2015 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wasserman</LastName><ForeName>Danuta</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden. Electronic address: danuta.wasserman@ki.se.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hoven</LastName><ForeName>Christina W</ForeName><Initials>CW</Initials><AffiliationInfo><Affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wasserman</LastName><ForeName>Camilla</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Medicine and Health Science, University of Molise, Campobasso, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wall</LastName><ForeName>Melanie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eisenberg</LastName><ForeName>Ruth</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Division of Child and Adolescent Psychiatry, New York State Psychiatric Institute, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hadlaczky</LastName><ForeName>Gergö</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelleher</LastName><ForeName>Ian</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sarchiapone</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine and Health Science, University of Molise, Campobasso, Italy; National Institute for Health, Migration and Poverty, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Apter</LastName><ForeName>Alan</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Feinberg Child Study Centre, Schneider Children's Medical Centre, Tel Aviv University, Tel Aviv, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Balazs</LastName><ForeName>Judit</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Budapest, Hungary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bobes</LastName><ForeName>Julio</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brunner</LastName><ForeName>Romuald</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Corcoran</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>National Suicide Research Foundation, Cork, Ireland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cosman</LastName><ForeName>Doina</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Clinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guillemin</LastName><ForeName>Francis</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Inserm CIC-EC, Nancy University Hospital, Nancy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haring</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institute for Clinical Evaluation, Department for Psychiatry and Psychotherapy B, State Hospital Hall, Tyrol, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iosue</LastName><ForeName>Miriam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medicine and Health Science, University of Molise, Campobasso, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaess</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Section for Disorders of Personality Development, Clinic of Child and Adolescent Psychiatry, Centre of Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kahn</LastName><ForeName>Jean-Pierre</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Nancy University Hospital, Nancy, France.</Affiliation></AffiliationInfo></Author><Author 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Slovenia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saiz</LastName><ForeName>Pilar</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, University of Oviedo, Oviedo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reiter-Theil</LastName><ForeName>Stella</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Clinical Ethics, Psychiatric Hospitals of the University of Basel, University Hospital Basel, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varnik</LastName><ForeName>Airi</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Varnik</LastName><ForeName>Peeter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Estonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia; Tallinn University, Tallinn, Estonia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carli</LastName><ForeName>Vladimir</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>DRKS</DataBankName><AccessionNumberList><AccessionNumber>DRKS00000214</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D016449">Randomized Controlled 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RefType="CommentIn"><RefSource>Lancet. 2015 Aug 29;386(9996):854</RefSource><PMID Version="1">26335877</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>Crisis. 2020 Jan;41(1):1-6</RefSource><PMID Version="1">31934796</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016000" MajorTopicYN="N">Cluster Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006266" MajorTopicYN="Y">Health Education</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017063" MajorTopicYN="N">Outcome Assessment, Health Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015397" MajorTopicYN="N">Program Evaluation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012572" MajorTopicYN="Y">School Health Services</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057566" MajorTopicYN="N">Self Report</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013405" MajorTopicYN="N">Suicide</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate 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